Signs of Periodontal Disease, Redness and bleeding of the gums when brushing, bad breath from food debris between shifting teeth positions these are just a few signs of periodontal disease. Its close association with other systemic diseases makes clinical management sensitive and complex. Special attention is needed for patients with cardiac conditions, anemia, diabetes, dyslipidemia, hormonal changes, and vitamin deficiencies. All these factors necessitate specialized treatment. If you have been treated for this disease before, regular check-ups and professional dental hygiene are advisable to monitor and maintain oral health.